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Tech

Artificial intelligence

Situational Awareness: The Decade AheadLeopold Aschenbrenner · 2024
AI 2027Kokotajlo, Alexander, Larsen, Lifland & Dean · 2025
Attention Is All You NeedVaswani et al. · 2017
Sparks of Artificial General Intelligence: Early Experiments with GPT-4Bubeck et al. · 2023

10 papersView all →

The CRISPR tool kit for genome editing and beyondAdli · 2018
Robust deep learning based protein sequence design using ProteinMPNNDauparas et al. · 2022

Domain Randomization for Transferring Deep Neural Networks from Simulation to the Real WorldTobin et al. · 2017
Soft robotics: new perspectives for robot bodyware and controlLaschi & Cianchetti · 2014

World Health Organization 2020 Guidelines on Physical Activity and Sedentary BehaviourBull et al. · 2020
Global Burden of 369 Diseases and Injuries in 204 Countries and Territories, 1990–2019GBD 2019 Collaborators · 2020

Short-term impacts of universal basic income on mental health inequalitiesThomson et al. · 2024
A national minimum wage reduced depressive symptoms in low-wage workersReeves et al. · 2016

Philosophy & society

Why Most Published Research Findings Are FalseJohn P. A. Ioannidis · 2005
Social Relationships and Mortality Risk: A Meta-analytic ReviewHolt-Lunstad, Smith & Layton · 2010

Climate & energy

Environmental and Health Impacts of Air Pollution: A ReviewManisalidis et al. · 2020
Mortality Risk Attributable to High and Low Ambient Temperature: A Multicountry Observational StudyGasparrini et al. · 2015

Airbnb2008 · Pre-Seed
Uber2008

Paul Graham essays

How to Do Great WorkPaul Graham
Having KidsPaul Graham

Collections

Leviathan (Chapters XIII–XVIII)Thomas Hobbes
Second Treatise of Government (Chapters II–V)John Locke
The Federalist No. 10James Madison
Democracy in America: Unlimited Power of the MajorityAlexis de Tocqueville

10 readingsView all →

Utilitarianism: What Utilitarianism IsJohn Stuart Mill
Fundamental Principles of the Metaphysic of Morals (First Section)Immanuel Kant
Beyond Good and Evil: What Is Noble?Friedrich Nietzsche
The Republic, Book IPlato

8 readingsView all →

The Wealth of Nations (Book I, Chapters I–III)Adam Smith
An Essay on the Principle of Population (Chapters 1–2)Thomas Robert Malthus
Progress and Poverty: Disproof of the Malthusian TheoryHenry George
The Theory of the Leisure Class: Conspicuous ConsumptionThorstein Veblen

10 readingsView all →

The Age of Reason (Part I, Chapters I–IX)Thomas Paine
Orthodoxy (The Maniac; The Suicide of Thought)G. K. Chesterton
Dialogues Concerning Natural Religion (Parts X–XI)David Hume
Why I Am an AgnosticRobert G. Ingersoll

9 readingsView all →

On the Origin of Species: Recapitulation and ConclusionCharles Darwin
In His Image: The Origin of ManWilliam Jennings Bryan
Mutual Aid (Introduction and Chapter I)Peter Kropotkin
The Struggle for Existence in Human SocietyThomas Henry Huxley

6 readingsView all →

Self-RelianceRalph Waldo Emerson
The Imitation of Christ (The First Book)Thomas à Kempis
Notes from Underground (Part I)Fyodor Dostoevsky
Walden: Where I Lived, and What I Lived ForHenry David Thoreau

7 readingsView all →

Books

CritoPlato
Civil DisobedienceHenry David Thoreau
Common SenseThomas Paine
Reflections on the Revolution in FranceEdmund Burke
No Treason No. VI: The Constitution of No AuthorityLysander Spooner
Southern Horrors: Lynch Law in All Its PhasesIda B. Wells-Barnett
The Soul of Man under SocialismOscar Wilde
Manifesto of the Communist PartyKarl Marx and Friedrich Engels
On Old AgeMarcus Tullius Cicero
ApologyPlato

Moderated Estimation of Fold Change and Dispersion for RNA-seq Data with DESeq2Love, Huber & Anders · 2014+15 points

Trimmomatic: A Flexible Trimmer for Illumina Sequence DataBolger, Lohse & Usadel · 2014+15 points

8 papersView all →

GelSight: high-resolution robot tactile sensors for estimating geometry and forceYuan, Dong & Adelson · 2017+15 points

OpenSim: Simulating Musculoskeletal Dynamics and Neuromuscular ControlSeth et al. · 2018+15 points

4 papersView all →

+15 points

Key challenges for delivering clinical impact with artificial intelligenceKelly et al. · 2019+15 points

Pivotal Trial of an Autonomous AI-based Diagnostic System for Detection of Diabetic RetinopathyAbràmoff et al. · 2018+15 points

8 papersView all →

+15 points

2 papersView all →

+15 points

The moral machine experiment on large language modelsTakemoto · 2024+15 points

Your robot therapist will see you nowFiske, Henningsen & Buyx · 2019+15 points

6 papersView all →

+15 points

Scientists’ warning to humanity: microorganisms and climate changeCavicchioli et al. · 2019+15 points

Present and future Köppen-Geiger climate classification maps at 1-km resolutionBeck et al. · 2018+15 points

4 papersView all →

Shopify2016

+10 points

Dropbox2007 · Pre-Seed+10 points

752 decksView all →

How to Lose Time and MoneyPaul Graham

+10 points

Lies We Tell KidsPaul Graham+10 points

233 essaysView all →

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